“Can Regenox improve jaw width (masseter hypertrophy) and fine lines?”
“What is the difference between Regenox and other botulinum toxin injections?”
If these are questions on your mind, read on.
Regenox is a botulinum toxin preparation that may help slim the face and improve the appearance of wrinkles.
As a generic equivalent of Allergan’s Botulinum Toxin Vista, it is offered at a lower price while being expected to deliver a comparable level of effect and duration.
This page outlines the effects and potential side effects of Regenox, as well as how it differs from other botulinum toxin injections.
At IC Clinic, we propose a treatment plan tailored to each individual patient and are committed to delivering results. We will take the time to listen carefully to your concerns and symptoms, so please use the button below to book a consultation.
Table of Contents
- 1 What Is Regenox? A Korean-Made Botulinum Toxin Preparation
- 2 Five Aesthetic Benefits You Can Expect from Regenox
- 2.1 Benefit ① Reducing Jaw Width and Achieving a Slimmer Face
- 2.2 Benefit ② Improving Wrinkles on the Forehead and Between the Brows
- 2.3 Benefit ③ Improving Underarm Hyperhidrosis and Axillary Osmidrosis
- 2.4 Benefit ④ Slimming the Calves for Leaner-Looking Legs
- 2.5 Benefit ⑤ Relieving Shoulder Stiffness
- 2.6 How Long Does Regenox Last? Duration Is Approximately 3–6 Months
- 3 Is the Treatment Painful? Side Effects and Contraindications of Regenox
- 3.1 Can Repeated Injections Lead to Antibody Formation That Reduces Effectiveness?
- 3.2 Is Contraception Required During Treatment? Contraception Is Advised During and for 2–4 Months After Treatment
- 4 Downtime After Regenox
- 5 Differences Between Regenox and Other Botulinum Toxin Injections Such as Those by Allergan
- 5.1 Botulinum Toxin Vista | Approved by Japan’s Ministry of Health, Labour and Welfare
- 5.2 Neuronox | Approved by Korea’s KFDA and Available at a Lower Cost
- 5.3 Bocouture (Xeomin) | Does Not Contain Complexing Proteins
- 5.4 Coretox | Lower Risk of Allergic Reactions
- 5.5 Innotox | Lower Risk of Bacterial Contamination
- 6 Regenox Pricing
- 7 Summary: Visit IC Clinic for Regenox Treatment
What Is Regenox? A Korean-Made Botulinum Toxin Preparation
Regenox (REGENOX) is a botulinum toxin injection that may help improve wrinkles and achieve a slimmer facial appearance.
It is a type of botulinum toxin preparation developed by South Korean company Hugel.
Botulinum toxin is a naturally occurring protein derived from the bacterium Clostridium botulinum found in nature. It works by reducing muscle activity, which may help improve jaw prominence and expression lines.
Regenox has been approved by the Korean Ministry of Food and Drug Safety (KFDA). It has been recognised as comparable in efficacy to the originator product, Allergan’s Botulinum Toxin Vista, and is provided at a lower price.
Five Aesthetic Benefits You Can Expect from Regenox
Regenox injections may offer the following aesthetic benefits:
- Reducing jaw width and achieving a slimmer face
- Improving wrinkles on the forehead and between the brows
- Improving underarm hyperhidrosis and axillary osmidrosis
- Slimming the calves for leaner-looking legs
- Relieving shoulder stiffness
In addition to facial areas, Regenox can be applied to various parts of the body, including the underarms, legs, and shoulders.
The following sections explain the specific benefits of each application area.
Benefit ① Reducing Jaw Width and Achieving a Slimmer Face
Botulinum toxin preparations such as Regenox are used to reduce jaw prominence. This treatment is commonly referred to as “jaw botulinum toxin” treatment.
A primary cause of a wide jaw is overdevelopment of the masseter muscle.
The masseter is the muscle mainly responsible for chewing. People who habitually grind their teeth or clench their back molars are more prone to tightening and enlargement of the masseter, which can make the jaw appear more prominent.
In jaw botulinum toxin treatment, the active ingredient botulinum toxin works to reduce the masseter muscle. This aims to make the jaw appear less prominent and to achieve a more defined facial contour.
Benefit ② Improving Wrinkles on the Forehead and Between the Brows
Regenox may help improve age-related expression lines.
Expression lines are wrinkles formed by the facial muscles when making expressions such as smiling or frowning.
While these wrinkles are originally temporary, repeated movement of the facial muscles can cause them to become permanent, making them visible even when the face is at rest.
By injecting Regenox, the movement of facial muscles is reduced, helping to improve wrinkles on the forehead and between the brows while maintaining a natural expression.
Benefit ③ Improving Underarm Hyperhidrosis and Axillary Osmidrosis
Injecting Regenox into the underarm area may help reduce sweat secretion and odour.
The two types of sweat glands responsible for underarm sweating and body odour are the eccrine glands and the apocrine glands.
Eccrine glands produce large amounts of clear, watery sweat, while apocrine glands produce sweat that contains odour-causing substances — each contributing to excessive underarm sweating and axillary odour respectively.
By acting on neurotransmitters, Regenox may suppress the secretion from both eccrine and apocrine glands, helping to improve hyperhidrosis and axillary osmidrosis.
Benefit ④ Slimming the Calves for Leaner-Looking Legs
Injecting Regenox into the calves may help you work towards slimmer-looking legs.
One of the reasons calves become bulkier is overdevelopment of the muscle.
People with athletic backgrounds or those who regularly wear high heels tend to be more prone to calf muscle hypertrophy.
The botulinum toxin in Regenox works to reduce hypertrophied muscles. Over time, this treatment may gradually reduce calf size, working towards targeted slimming of the legs.
Benefit ⑤ Relieving Shoulder Stiffness
Regenox can also be used to treat shoulder stiffness.
The trapezius muscle, which extends across the neck, shoulders, and back, plays a significant role in the development of shoulder stiffness.
For example, prolonged desk work can cause the trapezius to tighten, leading to shoulder pain.
In treatment with Regenox, the active ingredient botulinum toxin works to ease tension in the trapezius muscle, aiming to relieve shoulder stiffness.
How Long Does Regenox Last? Duration Is Approximately 3–6 Months
While results vary among individuals, Regenox generally lasts approximately 3 to 6 months.
Allergan’s Botulinum Toxin Vista has a duration of approximately 3 to 6 months. Regenox is expected to offer a similar duration to the originator product.
Please note that the effects of botulinum toxin preparations are not felt immediately after treatment.
As a general guide, improvements in expression lines may be noticeable within 2 to 3 days, while facial slimming effects typically become apparent 2 weeks to 1 month after treatment.
Is the Treatment Painful? Side Effects and Contraindications of Regenox
The main potential side effects of Regenox are as follows:
- Pain and swelling
- Bruising
- Reduced facial expressiveness
As a fine needle is used for the injection, significant pain or swelling is uncommon. In rare cases, bruising may occur, but this typically subsides within a few days.
Additionally, Regenox injections may cause the brows to lift unnaturally or result in reduced facial expression.
This occurs when the muscle-relaxing effect of botulinum toxin is more pronounced than intended. Careful adjustment of the injection volume is important to avoid over-correction.
Can Repeated Injections Lead to Antibody Formation That Reduces Effectiveness?
Repeated Regenox injections may lead to a reduction in effectiveness over time.
This is because the body’s immune system may respond to the active ingredient botulinum toxin and produce antibodies against it.
As the cumulative dose of botulinum toxin preparations increases, antibody production may become more likely.
To help minimise antibody formation, it is important to allow sufficient intervals between Regenox treatments and to use only the necessary amount per session.
Is Contraception Required During Treatment? Contraception Is Advised During and for 2–4 Months After Treatment
Both men and women are advised to use contraception during Regenox treatment and for a certain period afterwards.
This is because the active ingredient botulinum toxin may potentially affect the foetus.
As a general guideline, women should use contraception until the completion of their second menstrual period after treatment, and men should do so for 3 months after treatment.
Naturally, those who are pregnant or may be pregnant are not eligible for Regenox treatment.
Downtime After Regenox
Regenox is associated with minimal downtime from swelling or inflammation.
In rare cases, swelling or bruising may occur, but these generally become less noticeable within 1 to 2 weeks of treatment.
Showering is permitted on the day of treatment; however, prolonged bathing and strenuous exercise should be avoided until the following day.
As the downtime is relatively short, Regenox may be a suitable option for those with busy schedules such as work commitments.
Differences Between Regenox and Other Botulinum Toxin Injections Such as Those by Allergan
Regenox holds domestic approval in South Korea and is offered at a lower price than Allergan’s botulinum toxin injection.
The table below compares the characteristics of Regenox and other botulinum toxin injections.
| Product | Regenox | Botulinum Toxin Vista | Neuronox | Bocouture (Xeomin) |
Coretox | Innotox |
|---|---|---|---|---|---|---|
| Manufacturer | Hugel | Allergan | Medytox | Merz | Medytox | Medytox |
| Active Ingredient | Botulinum Toxin Type A | |||||
| Key Features | May offer long-lasting effects with a lower cost | Approved by Japan’s Ministry of Health, Labour and Welfare; widely used | Approved in South Korea; available at a lower cost | Does not contain complexing proteins | Lower risk of allergic reactions | Lower risk of bacterial contamination and preparation errors |
As shown above, Regenox is a Botulinum Toxin Type A preparation, the same as Allergan’s Botulinum Toxin Vista. The expected effect, duration, and likelihood of antibody formation are comparable between the two.
The following sections look at the characteristics of each product in more detail.
For a general overview of botulinum toxin injections, please also refer to our page “What Are Botulinum Toxin Injections? Five Aesthetic Benefits and Potential Side Effects to Consider.”
Botulinum Toxin Vista | Approved by Japan’s Ministry of Health, Labour and Welfare
Allergan’s Botulinum Toxin Vista holds approval from Japan’s Ministry of Health, Labour and Welfare, unlike other products in its category.
As the originator botulinum toxin preparation, it has been used in Japan for over a decade.
Originally a registered trademark of Allergan, “Botulinum Toxin” (ボツリヌス製剤) has since become widely used as a general term for botulinum toxin preparations.
As it has been used in over 60 countries worldwide, Botulinum Toxin Vista may be a suitable option for those seeking a botulinum toxin injection with a well-established track record.
For more information, please read “What Is Botulinum Toxin Vista? Differences from Botulax, Effects, and Side Effects Explained.”
Neuronox | Approved by Korea’s KFDA and Available at a Lower Cost
Neuronox is a product approved by the Korean Ministry of Food and Drug Safety (KFDA).
It is manufactured by South Korean company Medytox as a botulinum toxin preparation equivalent to a generic version of Allergan’s botulinum toxin product. As a generic equivalent, treatment costs are somewhat lower.
Neuronox also shows minimal difference in efficacy compared to Allergan’s botulinum toxin preparation.
For more information, please read “Neuronox: A Type of Jaw Botulinum Toxin Injection — Duration of Effect and Side Effects Explained.”
Bocouture (Xeomin) | Does Not Contain Complexing Proteins
Bocouture (Xeomin) has the characteristic of being less likely to trigger antibody formation even with repeated use.
Conventional botulinum toxin preparations carry a risk of antibody formation due to the complexing proteins they contain.
If antibodies develop, the effectiveness of botulinum toxin may diminish, making it more difficult to continue treatment.
As Bocouture contains virtually no complexing proteins, it may allow treatment with a reduced risk of antibody formation.
Coretox | Lower Risk of Allergic Reactions
Coretox is a preparation associated with a lower risk of allergic reactions and side effects.
Conventional botulinum toxin preparations contain human serum albumin as a preservative. Human serum albumin is a protein that has been associated with side effects such as fever and breathing difficulties.
As Coretox does not use human serum albumin and also contains no complexing proteins, it is characterised by a potentially lower risk of allergic reactions and side effects compared to other botulinum toxin preparations.
For more information, please read “Coretox: A Korean Botulinum Toxin Injection — Effects, Duration, and Differences from Neuronox Explained.”
Innotox | Lower Risk of Bacterial Contamination
Innotox is a preparation associated with a lower risk of bacterial contamination during preparation.
Conventional botulinum toxin preparations come in powder form and must be diluted with saline solution before injection. Given the possibility of bacterial contamination or preparation errors, the dilution process requires careful handling.
Innotox, by contrast, is a liquid preparation and therefore does not require dilution. This means it can be used with a reduced risk of bacterial contamination and preparation errors.
For more information, please read “What Is Innotox? Three Benefits, Duration, and Differences from Other Botulinum Toxin Injections Explained.”
Regenox Pricing
IC Clinic offers botulinum toxin injections using Regenox.
For detailed pricing, please refer to the relevant pages by treatment area:
- Wrinkle Treatment Pricing
- Facial Slimming & Contouring Pricing
- Underarm Odor (Axillary Osmidrosis) Pricing
- Hyperhidrosis Pricing
- Body Slimming Pricing
Summary: Visit IC Clinic for Regenox Treatment
Regenox is a type of botulinum toxin preparation used for concerns such as jaw prominence and wrinkles.
It is expected to offer comparable effects to Allergan’s Botulinum Toxin Vista, while being provided at a more accessible price.
At IC Clinic, we can propose Regenox treatment tailored to each patient’s individual concerns. Consultations are conducted in person, so please feel free to visit us at your convenience.
We propose a treatment plan suited to each individual patient and are committed to delivering results. We will take the time to listen carefully to your concerns and symptoms, so please use the button below to book a consultation.
