Adapalene Gel Explained: Treatment Effects for Acne, How It Differs from Differin, and How to Use It Correctly

“What effects does adapalene gel have?”
“I want to know about the effects and side effects of acne medications.”

If you have questions like these, read on.

Adapalene is the generic form of Differin. It helps clear clogged pores that cause acne, and works to prevent acne from worsening or new breakouts from forming.

This article explains the effects of adapalene (adapalene gel) and how it differs from Differin.

If you are concerned about acne or acne scars, please also refer to the articles below.

We introduce the types of acne and acne scars along with a comparison of treatment options, so you can explore the approach that best suits your concerns.

 

Types and Causes of Acne — Treatments and Pricing Explained

For treatment of acne scars such as crater scarring and post-inflammatory hyperpigmentation, see here. Learn more about IC Clinic’s acne treatment “Agnes.” At our clinic …

 

Types and Causes of Acne Scars — Treatments and Pricing Explained

For treating acne before it leaves marks — such as whiteheads and red pimples — see here. Learn more about IC Clinic’s acne scar treatment “Dermapen Microneedling.” At our clinic …

 

At our clinic, we propose a treatment plan tailored to each individual patient and provide care with a focus on results.
We take the time to listen carefully to your concerns and symptoms, so please use the button below to book a consultation.

Book Online Now

Table of Contents

  • 1 What Is Adapalene (Adapalene Gel)? A Medication That Helps Clear Clogged Pores
    • 1.1 How Does Adapalene Differ from Differin? Adapalene Gel Is a Generic Medication
    • 1.2 How Does Adapalene Differ from Benzoyl Peroxide? Their Actions on the Stratum Corneum Differ
    • 1.3 Adapalene Gel Does Not Contain Steroids
  • 2 Effects of Adapalene Gel | Helps Improve Whiteheads and Blackheads
    • 2.1 When Does Adapalene Gel Start Working? Effects May Take Around One Month to Appear
    • 2.2 Does Adapalene Gel Have Skin-Beautifying Effects? It Is Not Effective for Pigmented Spots or Acne Scars
  • 3 What Are the Side Effects of Adapalene Gel? These May Include Skin Dryness, Redness, and Itching
  • 4 How Should Adapalene Gel Be Used? Before or After Toner? Correct Application Explained
    • 4.1 Progress After Starting Adapalene Gel
    • 4.2 How Long Should You Continue Using Adapalene Gel? Continue for at Least One Year
    • 4.3 Are There People Who Should Not Use Adapalene Gel? It Cannot Be Used During Pregnancy
  • 5 Where Can You Get Adapalene Gel? It Is Not an Over-the-Counter Drug and Cannot Be Purchased Online
  • 6 Differences Between Adapalene Gel, Duac Gel, and Benzoyl Peroxide Gel (BPO)
  • 7 Please Visit a Medical Facility to Obtain and Use Adapalene Gel

What Is Adapalene (Adapalene Gel)? A Medication That Helps Clear Clogged Pores

Adapalene is an active ingredient used in acne medications.

“Adapalene gel,” which contains adapalene as its active ingredient, is a topical medication that helps clear clogged pores. It works to treat acne in its early stages and may help prevent inflammation from developing.

Acne is primarily caused by excess sebum accumulating in the pores. This sebum allows C. acnes bacteria to proliferate, leading to pore inflammation and the formation of pimples.

Acne progresses from whiteheads to blackheads and then to red pimples (papules). Adapalene gel is a treatment medication that may help improve whiteheads before acne advances further.

How Does Adapalene Differ from Differin? Adapalene Gel Is a Generic Medication

Differin is another acne treatment medication in the same category as adapalene gel. Adapalene gel is the generic version of Differin.

Since the active ingredient is the same adapalene, there is no difference in effects or side effects. However, adapalene gel, being a generic medication, is generally available at a lower price.

How Does Adapalene Differ from Benzoyl Peroxide? Their Actions on the Stratum Corneum Differ

Another ingredient often compared to adapalene is benzoyl peroxide (BPO).

Both adapalene and benzoyl peroxide are ingredients used in acne medications, but they work differently.

Ingredient Mechanism of Action
Adapalene Suppresses differentiation of cells at the pore opening to thin the stratum corneum. Has an action that helps dissolve comedones (plugs) that cause acne.
Benzoyl Peroxide Promotes exfoliation of the stratum corneum through a peeling action. Helps clear blockages at the pore opening, making it effective for acne treatment.

BPO Gel (benzoyl peroxide gel) is an example of an acne medication containing benzoyl peroxide.

Because acne medications may work differently for each individual, the prescription is tailored to your skin condition and the type of acne you have.

Adapalene Gel Does Not Contain Steroids

Steroids have an anti-inflammatory effect. However, adapalene gel does not contain any steroids.

There are acne medications that do contain steroids, but depending on the condition of the acne, they may potentially worsen it, so caution is advised.

Effects of Adapalene Gel | Helps Improve Whiteheads and Blackheads

Adapalene gel may help suppress keratinocyte differentiation and improve clogged pores.

Acne in its earliest stage has not yet become inflamed, but when C. acnes bacteria proliferate and cause inflammation, it progresses to red pimples (papules).

Pre-inflammatory acne includes whiteheads and blackheads, and adapalene gel may be helpful in addressing these. It is not expected to be effective for red or yellow pimples, pigmented spots, or similar concerns.

Adapalene has a mild peeling action and may also help improve the appearance of strawberry nose caused by blackheads.

When Does Adapalene Gel Start Working? Effects May Take Around One Month to Appear

Results from adapalene gel vary among individuals; however, in many cases acne gradually decreases after about 1 to 2 months of use.

If the area affected by acne is extensive, it may take approximately 3 months before a noticeable improvement is felt.

Does Adapalene Gel Have Skin-Beautifying Effects? It Is Not Effective for Pigmented Spots or Acne Scars

Adapalene has a structure similar to vitamin A derivatives. As a result, it may help make pores less noticeable while also working to refine skin texture.

However, adapalene gel is not expected to improve pigmented spots or acne scars.

Pigmented spots come in various types, and while there is a possibility of improvement in mild cases, this medication is not intended as a treatment for pigmented spots, so please keep this in mind.

If your goal is to improve pigmented spots or acne scars, please consider other treatment options.

What Are the Side Effects of Adapalene Gel? These May Include Skin Dryness, Redness, and Itching

The following side effects have been reported with adapalene gel:

  • Skin dryness
  • Erythema (redness)
  • Itching
  • Peeling

Side effects often persist for approximately two weeks to one month. There is also a possibility that acne may temporarily worsen after starting adapalene.

If side effects are severe, discontinue use of adapalene gel and consult a physician.

How Should Adapalene Gel Be Used? Before or After Toner? Correct Application Explained

Adapalene gel should be applied before bed, after washing your face. The specific steps are as follows:

  1. Cleanse your face
    Wash your face thoroughly with a facial cleanser before bed, then pat dry. Be careful not to rub the skin when drying.
  2. Apply adapalene gel
    Apply an appropriate amount around the affected area. When applying to the entire face, a guideline is the length from the tip of your index finger to the first knuckle (approximately 2 cm). Be careful not to apply too much.
  3. Wash your hands
    Wash your hands after applying the gel.

Adapalene is a medication applied once daily. Applying it multiple times a day is not recommended and should be avoided.

If you regularly use skincare products such as toner or emulsion, please apply adapalene gel after those steps.

Progress After Starting Adapalene Gel

The following describes the typical progress from the start of adapalene gel use:

Up to 2 weeks A period when skin irritation is commonly experienced. Symptoms such as skin dryness and a stinging sensation may occur.
1–2 months Effects begin to gradually appear, and acne slowly starts to decrease. Red pimples may form during this period, but it is important to continue daily use.
3 months onward The period when effects become more noticeable. Acne is significantly reduced. Even after acne clears, continuing treatment is important.

A stinging sensation and skin irritation are commonly experienced during the first two weeks of use.

After that, effects typically begin to be felt after 1 to 2 months. In many cases, acne has cleared considerably by the time 3 months have passed.

Continuing to use the gel even after acne has resolved may help prevent new breakouts from forming.

How Long Should You Continue Using Adapalene Gel? Continue for at Least One Year

It is recommended to continue using adapalene gel consistently for one year.

Because adapalene gel works to suppress acne formation, it may help reduce the occurrence of new pimples and prevent progression to red, inflamed acne.

If you stop using adapalene gel once your acne has cleared, new breakouts may begin to appear again.

However, if you do not notice any improvement after 3 months of use, discontinue use and consult your physician.

Are There People Who Should Not Use Adapalene Gel? It Cannot Be Used During Pregnancy

Adapalene gel cannot be used by those who are pregnant, those who may be pregnant, or those who are breastfeeding.

If you discover you are pregnant while using the gel, or if there is a possibility you may be pregnant, please consult a physician.

Additionally, adapalene gel has not been prescribed for children under 12 years of age due to a lack of usage data in this population.

Where Can You Get Adapalene Gel? It Is Not an Over-the-Counter Drug and Cannot Be Purchased Online

Adapalene gel is a prescription medication that can only be obtained and used with a doctor’s prescription. It is not available over the counter at pharmacies or drugstores.

Therefore, adapalene gel cannot be purchased through online retailers such as Amazon or Rakuten. While personal importation is possible, there are risks of counterfeit products and potential health hazards.

If you would like a prescription for adapalene gel, please visit a medical facility.

Differences Between Adapalene Gel, Duac Gel, and BPO Gel

In addition to adapalene gel, other acne treatment medications include Duac Gel and BPO Gel (benzoyl peroxide gel). The differences between these medications are as follows:

Adapalene Gel Duac Gel BPO Gel
Active Ingredient(s) · Adapalene · Benzoyl peroxide
· Clindamycin
· Benzoyl peroxide
Effects · Clears clogged pores
· Improves early-stage acne
· Helps prevent acne
· Improves red, inflamed acne · Clears clogged pores
· Improves acne
Side Effects · Dryness
· Redness
· Itching
· Peeling
· Itching
· Dryness
· Stinging
· Skin irritation / contact dermatitis
· Peeling
· Redness
· Stinging
· Peeling
· Dryness

There is no significant difference in the overall efficacy of these acne medications. However, since the active ingredients differ and suitability varies depending on your skin condition and the state of your acne, please decide on a medication in consultation with your physician.

For detailed information on Duac Gel and BPO Gel, please refer to the respective pages linked below.

What Is Duac Combination Gel? Effects, Side Effects, and Differences from Other Acne Medications Explained

What Is BPO Gel? Effects, Side Effects, and Usage for Acne Treatment Explained

Please Visit a Medical Facility to Obtain and Use Adapalene Gel

Adapalene gel is the generic version of Differin gel.

Adapalene gel may help suppress keratinocyte differentiation and improve clogged pores. Effects may begin to appear after 1 to 2 months, with gradual improvement in acne over time.

Additionally, the following side effects may occur with adapalene gel:

  • Skin dryness
  • Erythema (redness)
  • Itching
  • Peeling

If you want to address acne from its early stages or improve skin that is prone to breakouts, please consult a physician and ask about a prescription for adapalene.

If you are concerned about acne or acne scars, please also refer to the articles below.

We introduce the types of acne and acne scars along with a comparison of treatment options, so you can explore the approach that best suits your concerns.

 

Types and Causes of Acne — Treatments and Pricing Explained

Published: May 26, 2023 | Updated: June 9, 2023. For treatment of acne scars such as crater scarring and post-inflammatory hyperpigmentation, see here. Learn more about IC Clinic’s acne treatment “Agnes.” At our clinic …

 

Types and Causes of Acne Scars — Treatments and Pricing Explained

For treating acne before it leaves marks — such as whiteheads and red pimples — see here. Learn more about IC Clinic’s acne scar treatment “Dermapen Microneedling.” At our clinic …

 

At our clinic, we propose a treatment plan tailored to each individual patient and provide care with a focus on results.
We take the time to listen carefully to your concerns and symptoms, so please use the button below to book a consultation.

Book Online Now

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