“What is AGA mesotherapy?”
“I want to know about the effects, side effects, and costs of AGA mesotherapy.”
If these are questions on your mind, read on.
AGA mesotherapy (hair growth mesotherapy) is a treatment that involves directly injecting active ingredients into the scalp with the aim of addressing hair thinning and hair loss.
When used alongside oral or topical AGA medications, it may help shorten the time before results are noticed.
This page explains the potential effects, side effects, and treatment procedure for AGA mesotherapy. Reading through to the end will help you decide whether AGA mesotherapy is the right treatment for you.
At our clinic, we propose a treatment plan tailored to each individual patient and focus on delivering results.
We take the time to thoroughly understand your concerns and symptoms, so please book a consultation using the button below.
Table of Contents
- 1 What Is AGA Mesotherapy? A Hair Growth Treatment That Delivers Active Ingredients to the Scalp
- 1.1 Ingredients Used in AGA Mesotherapy (Hair Growth Mesotherapy)
- 1.2 Five Types of AGA Mesotherapy Treatment Methods
- 1.3 Differences Between AGA Mesotherapy and HARG+ Therapy
- 2 Potential Effects of AGA Mesotherapy
- 2.1 Effect ① Slowing the Progression of Hair Thinning
- 2.2 Effect ② Promoting Hair Growth
- 2.3 Is AGA Mesotherapy Ineffective on Its Own? Combining It with AGA Medications Is Recommended
- 2.4 How Many Sessions Before Results Appear? A Guide to the Number of Treatments
- 3 Advantages of AGA Mesotherapy
- 4 Disadvantages of AGA Mesotherapy
- 5 Side Effects of AGA Mesotherapy
- 6 AGA Mesotherapy Treatment Procedure
- 7 Progress and Aftercare Following AGA Mesotherapy
- 8 Cost of AGA Mesotherapy
- 9 Frequently Asked Questions About AGA Mesotherapy
- 9.1 Q. Is AGA Mesotherapy Painful?
- 9.2 Q. Can I Perform AGA Mesotherapy on Myself?
- 10 AGA Mesotherapy: A Treatment That Can Deliver Multiple Ingredients at Once
What Is AGA Mesotherapy? A Hair Growth Treatment That Delivers Active Ingredients to the Scalp

AGA mesotherapy (hair growth mesotherapy) is a treatment that involves directly injecting active ingredients into the scalp with the aim of addressing hair thinning and hair loss.
AGA treatment is primarily carried out using oral or topical medications. AGA mesotherapy, when used in combination with these medications, may help shorten the time before results are noticed.
Another feature of this treatment is that it uses ingredients that are not harmful to the body. It may be a viable option for patients who are unable to undergo medication-based treatment due to pre-existing conditions or individual constitution, and it is associated with fewer side effects compared with oral medications.
Ingredients Used in AGA Mesotherapy (Hair Growth Mesotherapy)
The ingredients used in AGA mesotherapy are those that may promote hair growth and support hair strengthening.
Please refer to the table below for the main components commonly included.
| Ingredient | Description |
|---|---|
| Minoxidil | Works to stimulate hair growth factors |
| Keratinocyte Growth Factor (KGF) | Supports the generation of epithelial cells and new hair |
| Insulin-like Growth Factor (IGF-1) | Supports new blood vessel regeneration and may enhance cellular regeneration |
| Vascular Endothelial Growth Factor (VEGF) | May promote new blood vessel formation and support hair thickening and growth |
| Basic Fibroblast Growth Factor (bFGF) | May increase the synthesis of collagen and elastin, supporting hair and skin cell growth |
| Copper Peptide | May help suppress male hormones |
In AGA mesotherapy, a blend of various ingredients is injected directly into the scalp with the aim of normalising the hair cycle and improving the scalp environment for hair growth.
Please note that the specific blend of ingredients used in AGA mesotherapy varies from clinic to clinic. We recommend confirming the ingredients to be used before undergoing treatment.
Five Types of AGA Mesotherapy Treatment Methods
AGA mesotherapy offers several methods of delivering ingredients to the scalp beyond the use of syringes.
The main treatment methods are the following five.
| Treatment Method | Delivery Method | Description |
|---|---|---|
| Papule Method | Syringe | Ingredients are injected directly into the scalp using a needle |
| Nappage Method | Syringe | Shallow injections into the surface of the scalp to deliver the solution to the subcutaneous tissue |
| Dermaroller Method | Roller with fine needles | Creates micro-channels in the skin to allow growth factors to penetrate |
| No-Needle Method | ・Electrical stimulation (pulses) ・Carbon dioxide |
Creates gaps in skin cell membranes and applies electrical pulses to the scalp surface |
| Fractional Laser Method | Laser irradiation | Delivers laser energy in micro-dot patterns to create small openings in the epidermis |
AGA mesotherapy methods that do not involve injections are characterised by minimal discomfort and reduced risk of bleeding.
In addition to the above, there is a similar treatment called “HARG+ therapy.” The following section explains HARG+ therapy in detail.
Differences Between AGA Mesotherapy and HARG+ Therapy

HARG+ therapy, like AGA mesotherapy, is a treatment that aims to promote hair growth by injecting active ingredients directly into the scalp.
The key differences between AGA mesotherapy and HARG+ therapy are as follows.
| AGA Mesotherapy | HARG+ Therapy | |
|---|---|---|
| Solution | A blend of the following three types of ingredients: ・Minoxidil ・Growth factors ・Hair growth factors |
HARG Cocktail (AAPE Powder) |
| Delivery Method | ・Syringe ・Roller with fine needles ・Pulses ・Carbon dioxide ・Laser etc. |
Syringe |
The primary difference between HARG+ therapy and AGA mesotherapy lies in the ingredients injected.
AGA mesotherapy uses a blend of ingredients formulated by the clinic, including components such as minoxidil, zinc, and minerals.
HARG+ therapy, on the other hand, uses “AAPE Powder” — a freeze-dried protein powder derived from adult adipose-derived stem cells. It contains over 150 types of growth factors and is also known as the “HARG Cocktail.”
While both are similar treatments, the main differences are the solution used and the delivery method. For more information about HARG+ therapy, please refer to the page below.
What Is HARG+ (HARG Plus) Therapy? A Look at Three Key Features, Pricing, and Treatment Duration
Potential Effects of AGA Mesotherapy

AGA mesotherapy may offer the following two potential benefits.
- Slowing the progression of hair thinning
- Promoting hair growth
AGA mesotherapy may offer similar benefits to oral AGA medications, but its distinguishing feature is its different approach — delivering ingredients directly to the scalp.
The following sections explain each potential effect in more detail.
Effect ① Slowing the Progression of Hair Thinning
When ingredients such as finasteride or dutasteride are administered via AGA mesotherapy, they may help slow the progression of hair thinning.
AGA is caused by DHT (dihydrotestosterone), a hormone that inhibits hair growth.
When DHT binds to androgen receptors, it disrupts the hair cycle, preventing hair from growing thick and leading to hair loss and thinning.
AGA mesotherapy works by inhibiting the binding of DHT to androgen receptors, thereby supporting a normalised hair cycle and helping to slow the progression of thinning and hair loss.
Effect ② Promoting Hair Growth
Minoxidil and growth factors contained in AGA mesotherapy solutions may help promote hair growth.
However, as stimulating hair growth alone is not sufficient to produce new hair, AGA mesotherapy solutions also include nutrients such as zinc and protein.
Where vitamins and minerals are included, the treatment may also help address hair thinning and loss caused by nutritional deficiencies, and support a scalp environment conducive to healthy hair growth.
Is AGA Mesotherapy Ineffective on Its Own? Combining It with AGA Medications Is Recommended

The current mainstream approach to AGA treatment involves oral and topical medications. AGA mesotherapy is generally not used as a standalone treatment, but rather in combination with medication-based therapy.
Combining AGA treatment with AGA mesotherapy may enhance the overall effectiveness of AGA care.
That said, it is important that AGA treatment be tailored to each individual patient. Please consult with your doctor to determine the approach that is right for you.
The page below provides more detailed information about AGA treatment medications.
AGA Treatment Medications: Effects, Side Effects, and Types of Oral and Topical Options
How Many Sessions Before Results Appear? A Guide to the Number of Treatments
As a general guide, one course of AGA mesotherapy consists of 6 to 16 sessions, with each course spanning approximately 6 months to one year.
Sessions are typically scheduled once every 2 to 4 weeks. In many cases, the effects of treatment begin to be noticed around 3 months after starting.
Please discuss with your doctor whether additional treatment courses are needed.
Advantages of AGA Mesotherapy

The main advantages of AGA mesotherapy are the following two.
- May be effective for female hair thinning as well
- Ongoing sessions may support sustained results
Because AGA mesotherapy allows ingredients to be blended according to each patient’s individual condition, it is a treatment that may also be beneficial for women experiencing hair thinning.
When used in combination with oral or topical AGA medications, it may also help shorten the time before results are noticed. A lower risk of side effects compared with medication-based treatment is another potential advantage worth noting.
Disadvantages of AGA Mesotherapy

The following three points are commonly cited as disadvantages of AGA mesotherapy.
- Requires regular visits to the clinic
- Tends to be more costly than oral or topical medications
- May not be effective when hair follicles are no longer present
As AGA mesotherapy involves a doctor injecting active ingredients directly into the scalp, one drawback is that the per-session cost is higher than medication-based treatment.
AGA mesotherapy is also not suitable for patients with cancer, as the active ingredients could potentially stimulate the growth of cancer cells.
Additionally, because AGA mesotherapy works by supporting hair growth, please be aware that results may not be achievable for patients whose AGA has progressed to the point where hair follicles are no longer present.
Side Effects of AGA Mesotherapy
AGA mesotherapy is considered a treatment with a relatively low likelihood of side effects. However, side effects cannot be ruled out entirely.
Possible side effects include the following.
- Itching or swelling at the treatment site
- Sensation of warmth
- Lumps or nodules
- Allergic reactions
- Anaphylactic shock
and others.
Redness or swelling around the treatment area may occur immediately after the procedure. These reactions typically subside within a few hours to a few days.
If side effects persist, please consult your doctor for guidance. Making decisions about your treatment plan on your own may pose health risks, so please visit the clinic for an assessment.
AGA Mesotherapy Treatment Procedure

AGA treatment at our clinic follows the steps below.
- Consultation and Examination
We begin by listening carefully to your concerns. We take the time to understand the specific issues each patient wishes to address and work together to determine a treatment plan. - Treatment and Procedure
Your doctor will inject a tailored blend of active ingredients directly into the scalp. - Aftercare
You will generally be able to resume your normal daily activities after treatment. Depending on the condition of the treatment site, we may advise you to avoid bathing or using a sauna for a period of time.
If you are considering AGA mesotherapy, please feel free to get in touch with IC Clinic.
Progress and Aftercare Following AGA Mesotherapy
You will generally be able to resume your normal daily activities after AGA mesotherapy. However, if redness or swelling is present at the treatment site, please avoid bathing or using a sauna until it has settled.
Consistent, ongoing treatment is important for addressing hair thinning and loss. Rather than stopping after a single session, please consider scheduling treatments at the recommended frequency of once every 2 to 4 sessions.
Please consult your doctor regarding whether additional treatment is needed.
Cost of AGA Mesotherapy
The cost of AGA mesotherapy at our clinic varies depending on the treatment course selected.
For specific pricing details, please refer to the AGA / FAGA / Hair Thinning price list.
Frequently Asked Questions About AGA Mesotherapy

Here we address some frequently asked questions about AGA mesotherapy.
Q. Is AGA Mesotherapy Painful?
The level of discomfort experienced during AGA mesotherapy varies depending on the treatment method used.
The differences in discomfort by method are as follows.
| Treatment Method | Expected Level of Discomfort |
|---|---|
| Papule Method | May involve some discomfort, as the solution is injected between the epidermis and dermis |
| Nappage Method | Minimal discomfort |
| Dermaroller Method | Less discomfort and bleeding than with a syringe |
| No-Needle Method | Little to no discomfort |
| Fractional Laser Method | Little to no discomfort |
If you have concerns about discomfort during AGA mesotherapy, please consult with the clinic in advance.
Q. Can I Perform AGA Mesotherapy on Myself?
It is possible to use self-care products at home that are marketed for similar purposes.
However, we do not recommend this for the following two reasons.
- The effectiveness of over-the-counter products cannot be guaranteed
- The needles on consumer dermarollers may have an adverse effect on the scalp environment
Performing AGA mesotherapy at home carries uncertain efficacy and potential risks. We strongly encourage you to consult a clinic for AGA treatment.
AGA Mesotherapy: A Treatment That Can Deliver Multiple Ingredients at Once
AGA mesotherapy (hair growth mesotherapy) is a treatment that involves directly injecting active ingredients into the scalp with the aim of addressing hair thinning and hair loss.
The two potential effects of AGA mesotherapy are as follows.
- Slowing the progression of hair thinning
- Promoting hair growth
Combining AGA mesotherapy with medication-based treatment may further enhance the effectiveness of AGA care.
At our clinic, we listen carefully to each patient’s concerns and propose a treatment plan suited to their individual needs. If you are considering AGA mesotherapy, we invite you to explore treatment options at IC Clinic.
We propose a treatment plan tailored to each individual patient and focus on delivering results.
We take the time to thoroughly understand your concerns and symptoms, so please book a consultation using the button below.